“Acceptance Speech” Frontiers of Knowledge Award 2023 in Biology and Biomedicine
John Michael Jumper
Acceptance speech by John Michael Jumper, winner of the 2023 Frontiers of Knowledge Award in Biology and Biomedicine, who was honored alongside David Baker and Demis Hassabis for their contributions to the use of artificial intelligence to accurately predict the three-dimensional structure of proteins. Jumper and Hassabis developed AlphaFold2, a deep learning system that has revolutionized structural biology by enabling protein structures to be predicted with unprecedented accuracy and speed.
Jumper explains how the DeepMind team combined biological knowledge with machine learning techniques to overcome the limitations of traditional protein structure prediction methods. He highlights AlphaFold’s applications in studying molecular complexes, engineering proteins and developing new therapies, including potential approaches to cancer treatment. He also emphasizes the importance of